Originalartikel | erschienen - Druck | peer reviewed | Open Access
Menopause is associated with obstructive sleep apnea in a population-based sample from Mecklenburg-Western Pomerania, Germany
Journal of Clinical Medicine
2023 / March
;
12(6):
2101 -
https://pubmed.ncbi.nlm.nih.gov/36983104[PubMed] https://www.mdpi.com/2077-0383/12/6/2101
Authors
Krüger M*1, Obst A2, Ittermann T3, Bernhardt O4, Ivanovska T, Zygmunt M5, Ewert R6, Fietze I, Penzel T, Biffar R1, Daboul A1
Affiliations
1 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Zahnärztliche Prothetik, Alterszahnheilkunde und Medizinische Werkstoffkunde
2 - Zentrum für Innere Medizin / Klinik für Innere Medizin B / Pulmologie
3 - Institut für Community Medicine / Abt. SHIP KEF
4 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Zahnerhaltung,Parodontologie, Endodontologie; Präventive Zahnmedizin und Kinderzahnheilkunde
5 - Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe
6 - Zentrum für Innere Medizin / Klinik für Innere Medizin B
Abstract
Objective
Menopause is associated with multiple health risks. In several studies a higher incidence or a higher risk for obstructive sleep apnea (OSA) in post-menopausal than pre-menopausal women is reported. This study was designed to verify such a connection between menopause and OSA in a population-based sample.
Methods
For a subsample (N = 1,209) of the Study of Health in Pomerania (N = 4,420) complete polysomnography data was available. Of these, 559 females completed a structured interview about their menstrual cycle. Splines and ordinal regression analysis were used to analyze the resulting data.
Results
In an ordinal regression analysis, a significant association between the apnea-hypopnea index (AHI) and the menopause indicated that post-menopausal women had a substantial higher risk of OSA. In accordance with previous studies risk indicators as body-mass-index (BMI), age,
and the influence of hysterectomies or total oophorectomies were included in the model.
Conclusion
Our results clearly confirmed the assumed connection between the menopause and OSA. This is important because OSA is most often associated with male patients and it warrants further research in the underlying mechanisms.
Published in
Journal of Clinical Medicine
Year | 2023 |
Month/Hj | March |
Impact Factor (2023) | |
Volume | 12 |
Issue | 6 |
Pages | 2101 - |
Open Access | ja |
Peer reviewed | ja |
Article type | Originalartikel |
Article state | erschienen - Druck |
DOI | 10.3390/jcm12062101 |
PubMed-ID | 36983104 |
Common journal data
Short name: J CLIN MED
ISSN: ****-****
eISSN: 2077-0383
Country: SWITZERLAND
Language: English
Categories:
Impact factor trend
ISSN: ****-****
eISSN: 2077-0383
Country: SWITZERLAND
Language: English
Categories:
- MEDICINE, GENERAL & INTERNAL
Impact factor trend
Year | Impact Factor |
---|---|
2017 | 5.583 |
2018 | 5.688 |
2019 | 3.303 |
2020 | 4.242 |
2021 | 4.964 |