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 Research Information System University of Greifswald

Originalartikel | erschienen - Druck | peer reviewed | Open Access

Menopause is associated with obstructive sleep apnea in a population-based sample from Mecklenburg-Western Pomerania, Germany

Journal of Clinical Medicine 2023 / March ; 12(6): 2101 -

https://pubmed.ncbi.nlm.nih.gov/36983104[PubMed] https://www.mdpi.com/2077-0383/12/6/2101

Bibliometric indicators

Citations (WOS) = 0

DOI = 10.3390/jcm12062101

PubMed-ID = 36983104


Krüger M*1, Obst A2, Ittermann T3, Bernhardt O4, Ivanovska T, Zygmunt M5, Ewert R6, Fietze I, Penzel T, Biffar R1, Daboul A1


Objective Menopause is associated with multiple health risks. In several studies a higher incidence or a higher risk for obstructive sleep apnea (OSA) in post-menopausal than pre-menopausal women is reported. This study was designed to verify such a connection between menopause and OSA in a population-based sample. Methods For a subsample (N = 1,209) of the Study of Health in Pomerania (N = 4,420) complete polysomnography data was available. Of these, 559 females completed a structured interview about their menstrual cycle. Splines and ordinal regression analysis were used to analyze the resulting data. Results In an ordinal regression analysis, a significant association between the apnea-hypopnea index (AHI) and the menopause indicated that post-menopausal women had a substantial higher risk of OSA. In accordance with previous studies risk indicators as body-mass-index (BMI), age, and the influence of hysterectomies or total oophorectomies were included in the model. Conclusion Our results clearly confirmed the assumed connection between the menopause and OSA. This is important because OSA is most often associated with male patients and it warrants further research in the underlying mechanisms.

Published in

Journal of Clinical Medicine

Year 2023
Month/Hj March
Impact Factor (2023)
Volume 12
Issue 6
Pages 2101 -
Open Access ja
Peer reviewed ja
Article type Originalartikel
Article state erschienen - Druck
DOI 10.3390/jcm12062101
PubMed-ID 36983104

Common journal data

Short name: J CLIN MED
ISSN: ****-****
eISSN: 2077-0383
Language: English

Impact factor trend

Year Impact Factor
2017 5.583
2018 5.688
2019 3.303
2020 4.242
2021 4.964

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