Originalartikel | erschienen - EPub | peer reviewed | Open Access
Prevalence and risk factors of potentially malignant disorders of the mucosa in the general population: Mucosa lesions a general health problem?
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
2021 ;
237(151724):
Bibliometric indicators
Impact Factor = 2.976
Citations (WOS) = 5
DOI = 10.1016/j.aanat.2021.151724
PubMed-ID = 33798694
Authors
Kindler S*1, Samietz S*2, Dickel S1, Mksoud M1, Kocher T3, Lucas C1, Seebauer C1, Doberschütz P4, Holtfreter B3, Völzke H5, Metelmann H1, Ittermann T5
Affiliations
1 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie/Plastische Operationen
2 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Zahnärztliche Prothetik, Alterszahnheilkunde und Medizinische Werkstoffkunde
3 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Zahnerhaltung,Parodontologie, Endodontologie; Präventive Zahnmedizin und Kinderzahnheilkunde
4 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Kieferorthopädie
5 - Institut für Community Medicine / Abt. SHIP KEF
Abstract
Aim: Oral cancer mostly develops from oral mucosa regions with morphological alterations transforming malignant. These visible precancerous mucosa lesions are named potentially malignant disorders (PMD). We aimed to analyze the prevalence of PMD and its risk factors for PMD in a population-based sample in Northern Germany.
Material and methods: Data of 6078 individuals from the population-based Study of Health in Pomerania (SHIP) was used. PMD were photographically documented and periodontal health was assessed in a standardized procedure.
Results: PMD were observed in 54 individuals (0.9%). The most prevalent PMD was homogenous leukoplakia (n = 37) followed by Lichen ruber (n = 9). Smoking (Odds Ratio (OR) 2.70; 95% confidence interval (CI): 1.24-5.87), male sex (OR 3.32; 95%-CI: 1.77-6.21), type 2 diabetes mellitus (OR 2.07; 95%-CI: 1.08-3.98) and body mass index (OR 1.09; CI 1.04-1.14) were significantly associated with PMD, with the corresponding area under the curve (AUC) being 0.696 (CI: 0.655; 0.737).
Conclusion: Our results suggest a clinically relevant prevalence of PMD in the population. We identified male sex, type 2 diabetes mellitus, current smoking, and obesity as risk factors. We recommend photographic documentation and intensified training of medical and dental staff to detect and monitor PMD.
Published in
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
Year | 2021 |
Impact Factor (2021) | 2.976 |
Volume | 237 |
Issue | 151724 |
Pages | - |
Open Access | ja |
Peer reviewed | ja |
Article type | Originalartikel |
Article state | erschienen - EPub |
DOI | 10.1016/j.aanat.2021.151724 |
PubMed-ID | 33798694 |
Common journal data
Short name: ANN ANAT
ISSN: 0940-9602
eISSN: 1618-0402
Country: GERMANY (FED REP GER)
Language: English
Categories:
Impact factor trend
ISSN: 0940-9602
eISSN: 1618-0402
Country: GERMANY (FED REP GER)
Language: English
Categories:
- ANATOMY & MORPHOLOGY
Impact factor trend
Year | Impact Factor |
---|---|
2008 | 0.932 |
2009 | 0.877 |
2010 | 1.658 |
2011 | 1.861 |
2012 | 1.96 |
2013 | 2.075 |
2014 | 1.483 |
2015 | 1.308 |
2016 | 1.864 |
2017 | 1.852 |
2018 | 2.241 |
2019 | 2.388 |
2020 | 2.698 |
2021 | 2.976 |
Departments
Community Medicine
Zahnheilkunde
Zahnheilkunde