Originalartikel | erschienen - Druck | peer reviewed | Open Access
Periodontitis Is Related to Exercise Capacity: Two Cross-sectional Studies.
JOURNAL OF DENTAL RESEARCH
2021 ;
100(8):
824 - 832
http://www.ncbi.nlm.nih.gov/pubmed/33655783[PubMed]
Bibliometric indicators
Impact Factor = 8.924
Citations (WOS) = 4
DOI = 10.1177/0022034521995428
PubMed-ID = 33655783
Authors
Holtfreter B*1, Stubbe B2, Gläser S2, Trabandt J3, Völzke H4, Ewert R2, Kocher T1, Ittermann T4, Schäper C2
Affiliations
1 - Zentrum für Zahn-, Mund- und Kieferheilkunde / Poliklinik für Zahnerhaltung,Parodontologie, Endodontologie; Präventive Zahnmedizin und Kinderzahnheilkunde
2 - Zentrum für Innere Medizin / Klinik für Innere Medizin B
3 - Zentrum für Innere Medizin / Klinik für Innere Medizin A
4 - Institut für Community Medicine / Abt. SHIP KEF
Abstract
Although a potential link between periodontitis and cardiorespiratory fitness might provide a reasonable explanation for effects of tooth-related alterations seen on cardiometabolic diseases, evidence is currently limited. Thus, we investigated the association between clinically assessed periodontitis and cardiopulmonary exercise testing (CPET). Data from 2 independent cross-sectional population-based studies (5-y follow-up of the Study of Health in Pomerania [SHIP-1; = 1,639] and SHIP-Trend-0 [ = 2,439]) were analyzed. Participants received a half-mouth periodontal examination, and teeth were counted. CPET was based on symptom limited-exercise tests on a bicycle ergometer. Associations of periodontitis parameters with CPET parameters were analyzed by confounder-adjusted multivariable linear regression. In the total sample, mean pocket probing depth (PPD), mean clinical attachment levels, and number of teeth were consistently associated with peak oxygen uptake (peakVO) and exercise duration in both studies, even after restriction to cardiorespiratory healthy participants. Statistically significant associations with oxygen uptake at anaerobic threshold (VO@AT), slope of the efficiency of ventilation in removing carbon dioxide, and peak oxygen pulse (VÉ/VCO slope) occurred. Further, interactions with age were identified, such that mainly older individuals with higher levels of periodontal disease severity were associated with lower peakVO. Restricted to never smokers, associations with mean clinical attachment levels and the number of teeth mostly diminished, while associations of mean PPD with peakVO, VO@AT, VÉ/VCO slope, and exercise duration in SHIP-1 and SHIP-Trend-0 were confirmed. In SHIP-1, mean peakVO was 1,895 mL/min in participants with a mean PPD of 1.6 mm and 1,809 mL/min in participants with a mean PPD of 3.7 mm. To conclude, only mean PPD reflecting current disease severity was consistently linked to cardiorespiratory fitness in 2 cross-sectional samples of the general population. If confirmed in well-designed large-scale longitudinal studies, the association between periodontitis and cardiorespiratory fitness might provide a biologically plausible mechanism linking periodontitis with cardiometabolic diseases.
Published in
JOURNAL OF DENTAL RESEARCH
Year | 2021 |
Impact Factor (2021) | 8.924 |
Volume | 100 |
Issue | 8 |
Pages | 824 - 832 |
Open Access | ja |
Peer reviewed | ja |
Article type | Originalartikel |
Article state | erschienen - Druck |
DOI | 10.1177/0022034521995428 |
PubMed-ID | 33655783 |
Common journal data
Short name: J DENT RES
ISSN: 0022-0345
eISSN: 1544-0591
Country: USA
Language: English
Categories:
Impact factor trend
ISSN: 0022-0345
eISSN: 1544-0591
Country: USA
Language: English
Categories:
- DENTISTRY, ORAL SURGERY & MEDICINE
Impact factor trend
Year | Impact Factor |
---|---|
2008 | 3.142 |
2009 | 3.458 |
2010 | 3.773 |
2011 | 3.486 |
2012 | 3.826 |
2013 | 4.144 |
2014 | 4.139 |
2015 | 4.602 |
2016 | 4.755 |
2017 | 5.38 |
2018 | 5.125 |
2019 | 4.914 |
2020 | 6.116 |
2021 | 8.924 |
Departments
Community Medicine
Herz- Kreislauferkrankungen
Zahnheilkunde
Herz- Kreislauferkrankungen
Zahnheilkunde